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Evidence-Based Validation of Herbal Medicine by Unknown

Author:Unknown , Date: March 19, 2021 ,Views: 174

Evidence-Based Validation of Herbal Medicine by Unknown

Author:Unknown
Language: eng
Format: epub
Publisher: Elsevier
Published: 2015-02-20T00:36:14+00:00


Chapter 13

Evaluation of Bioactive Compounds as Acetylcholinesterase Inhibitors from Medicinal Plants

Santanu Bhadra, Manoj K. Dalai, Joydeb Chanda, and Pulok K. Mukherjee School of Natural Product Studies, Department of Pharmaceutical Technology, Jadavpur University, Kolkata, India

Abstract

The predominant role of the central cholinergic pathway in learning and memory and the creation of severe cholinergic deficits with several neurodegenerative disorders and cognitive impairment contribute to the development of symptomatic cholinergic therapy. Inhibition of brain cholinesterase (ChE) serves as a strategy for the treatment of several cognitive diseases such as Alzheimer disease (AD), senile dementia, ataxia, myasthenia gravis, glaucoma, and Parkinson disease. ChE inhibitors are the drugs for the management of AD-type of dementia. The chapter highlights on acetylcholinesterase inhibitors from plants and the phytoconstituents derived from this.



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